The skin has a protective fatty outer layer known as the lipid barrier, which is responsible for retaining moisture in the skin while ensuring that potentially harmful elements do not penetrate the skin. A thin, weaker, and compromised lipid barrier can result in sensitive, reactive skin. It is easier now for irritants to penetrate the skin and cause inflammation.

One can try to avoid external trauma to the skin, as well as certain illnesses that may trigger it, but there are some chronic and genetic conditions that predispose the skin to a state of inflammation no matter what precautions are taken.



Itch-Scratch Cycle

Atopic Dermatitis causes a significant itch, which naturally motivates the behavior of scratching. However, scratching can cause complications: scratching further damages the skin barrier, leading to a worsening of symptoms, thickened patches of skin, and increasing the risk of infection. In addition, scratching at night can cause disruption to sleep, as people with (AD) may wake repeatedly during the night to scratch due to excessive itchiness. The repeated waking and loss of sleep is one of the most distressing impacts of (AD) on children living with the condition, as well as their family members.